I agree with some of what Velusion is saying

temperature is only used if you have some sort heat(or cold) source, so it depends on what you're doing... Just what kind of effect are you doing? Smoke, fire..??

Your system will get bogged down, there's no way around it, even on a workstation it will bog down, thats the price of having good looking fluids and you have to be willing to make that sacrifice sometimes. There is such a thing though as going too high of a resolution, and for smoke you don't need high resolutions...

You don't need to touch your density scale, but you do need to fool around with your opacity ramp and raise the boyancy of your density, but leave the gravity at its default 9.8....also put a damp of .005 on it, its always good to sort of dampen things to "keep it real"

The opacity ramp... From left to right is 0 to 1 outside to inside and how many points you add depends on what you're doing. Transparency and Opacity go hand in hand for this particular effect.

you need some sort of dissipation on the density, for this I recommend about .15... you need a little bit of turbulence to throw and mix around, .03 would be good for this, any more than .1 and it will throw your fluids around too much....

Now depending on what you're doing, you will set the resolution accordingly, don't forget that you can use the normal scale tool also, you just have to raise or lower your resolution as needed, but you can also use extend fluids, that also depends on the situation.

Just what effect are you doing with fluids? Smoke? Fire? Dry Ice? .....