With the wrap you can just pose the model, then switch the geos to see whats its like rarter than smoothing and going backwards and forwards with the smooth node. Its pretty good practice as if you say make a low poly model then smooth it, and then Zbrush it bringing in maybe a higher res with a displacmement map it would be a bugger to animate with so using a wrap deformer gives you the freedom to animate with speed but still keep the lovelyness of the high poly model work.
You can also use blendshapes, influence objects to make muscle deformations that are then taken onto the high poly model only using the high poly at render time.
End of the day its up to you, you can use it for animating pretty much anything (eg a car, have the high poly driven by a really low poly model as the stand in.)
"No pressure, no diamonds" Thomas Carlyle